Further comparative analysis with gene ontology terms from a human cardiac organoid infarction model [24] (compared to normoxia control) revealed alignment of processes across these studies to support ischaemic cardiac injury, including muscle/heart contraction (GO:0006936/GO:0060047; human myocardial infarction) (proteins identified in the current study for this network included SCN5A, TNNI3, DES, NPPA, FGF12, ATP2B4, ATP1A1, GAA, RYR1, ANK2, MYH3) and cardiac muscle contraction (GO:0060048; mouse myocardial infarction) (Data file S2C—D). The gene discussed is NPPA; the disease is myocardial infarction.