Based on the long‐term in‐depth research on this topic, our previous study shown that VAD exacerbated ovalbumin‐induced asthma in mice, with increased lung inflammation and increased expression of type 2 cytokines and IgE, possibly due in part to group 2 innate lymphoid cells (ILC2s) proliferation and activation (Cui et al. 2016). This evidence concerns the gene IGHE and asthma.