IGF1 and pituitary tumor: Acromegaly is a secondary entity to the overproduction of growth hormone (GH), in more than 95% of cases due to a pituitary tumor; the final consequence of this overproduction of GH is the induction of insulin-like growth factor 1 (IGF-1), which is the molecule that generates the peripheral effect in tissues and systems, producing important metabolic and morphological changes in the patient [1].