An initial study with a sample size of 70 patients[113] calculated the percentage, partial function, and clinical relevance of circulating MAIT cells in lung cancer patients, and found that the concentration of activated CD38+CD8+MAIT cells in the peripheral blood of lung cancer patients was elevated, and it was positively correlated with IL-6, indicating an immunosuppressive function and affecting the PFS of patients. This evidence concerns the gene CD38 and lung cancer.