Mutations in the somatic variant of mtDNA in the MT-RNR1 gene, 709G > A and MT-CR, 195T > C were also observed in patients with ovarian and prostate cancer, glioblastomas, noninvasive thyroid follicular neoplasms, and nasopharyngeal tumors[34-37]. The gene discussed is MT-RNR1; the disease is glioblastoma.