CBL and melanoma: While this variant did not show significant allelic cis-regulatory potential via MPRA, fine-mapped variants at this locus are indeed eQTLs for CBL in melanocytes (P = 0.02 to 0.008 for the four variants targeted by CRISPRi; Figure S14; Table S21), suggesting the potential for shared causal variants between melanoma risk and germline regulation of CBL expression at this locus.