These regulators participate in key biological processes, including metabolic reprogramming (e.g., glycolysis, glutaminolysis, and lipid metabolism), biosynthetic pathways (e.g., ribosome and nucleic acid synthesis), signaling pathway regulation (e.g., PI3K/AKT/mTOR), and cell cycle control, which all affect tumor proliferation. The gene discussed is AKT1; the disease is neoplasm.