For example, in gastric cancer, B cells within TLSs promote glycolysis in CD103+CD8+ TRM cells through the lymphotoxin‐α (LTα)/tumor necrosis factor receptor 2 (TNFR2) signaling axis, increasing their metabolic adaptability and thereby boosting the effector functions of TRM cells for an effective antitumor response.81 The gene discussed is CD8A; the disease is gastric cancer.