CRP and rheumatoid arthritis: However, it should be noted that there are limitations in the disease activity evaluation tools and studies have shown that RA patients with swollen joints can still suffer further joint damage even when their DAS28 score is less than 2.6.[51] In 2011, the ACR and EULAR proposed Boolean remission criteria, which included tender joint count, swollen joint count, C-reactive protein (CRP) level, and patient global assessment were all ≤ 1.[52] Due to its high specificity and the ease of implementation, the criteria has been gradually adopted in clinical practice.