YWHAH and rheumatoid arthritis: The data from Wang et al. support our findings, which show that 14-3-3 Eta protein functions as a sensitive and specific biomarker for RA, with an area under the curve of 0.9245 and a pooled sensitivity and specificity of 0.73 (95% CI: 0.71–0.75) .[28] In reference to JIA Risha et al. revealed that the serum 14-3-3 Eta protein RO) has been found to have 84% sensitivity, 55% specificity, 65.6% PPV, and 69.2% NPV among all JIA subgroup patients at levels greater than 1.45 μg/L [2]