Various MDM2 inhibitors, such as SAR405838 (MI-77301), MK-8242, MI-63, RG7388 (RO5503781), RG7112 (RO5045337), and RG7775 (RO6839921), have also exhibited potential in stabilizing p53 and inducing apoptosis in neuroblastoma cells.28 This evidence concerns the gene MDM2 and neuroblastoma.