Relative to healthy controls, post-mortem NP2 mRNA levels in the schizophrenia group showed reductions throughout all four cortical regions of the vsWM network, thus suggesting the impaired activity of pyramidal neurons and the alterations in parvalbumin (PV) and somatostatin (SST) inhibitory neurons observed in schizophrenia [47]. The gene discussed is NPTX2; the disease is schizophrenia.