EZH2 and acute myeloid leukemia: Further, it also inhibits trimethylation of lysine 27 on H3 (H3K27me3) and lysine 20 on H4 (H4K20me3), which was proved when treated on human acute myeloid leukemia cells (HL‐60 and OCI‐AML3 cells) and involves in depletion of EZH2.190