Insufficient improvement in the immunosuppressive TME, especially the phenotype of tumor‐associated macrophages (Figures S8a–c) and reduction in the amount of CD8+ T cells (Figures S8e) at the time of analysis, are considered to be the reasons why the anti‐tumor effect of NE/CAMP+aPD‐1 was only slightly increased by aPD‐1 combination compared with NE/CAMP alone. This evidence concerns the gene CAMP and neoplasm.