Given the ability of commensal microbes to trigger T‐cell responses (Wegorzewska et al. 2019), efforts have been made to engineer the skin symbiotic strain Staphylococcus epidermidis to express melanoma‐associated antigens, aiming to increase melanoma antigen‐specific CD8+ T cells and enhance tumour cell killing (Chen et al. 2023). Here, CD8A is linked to melanoma.