CDK20 and liver cancer: CDK20 (CCRK) is possibly implicated in cell cycle regulation and progression across various cancer types, including glioblastoma, liver cancer, ovarian cancer, and colorectal cancer.232,429 CDK20 is commonly overexpressed in cancer, correlating with poor prognosis and tumor staging, although mutations in its gene are infrequent.232,429 The exact mechanism underlying CDK20 upregulation and its oncogenic properties varies across different tissue types.232,429