CD274 and neoplasm: In the full analysis set, the median age was 61.9 years (range 31–79) and most patients were men (411 [82.9%]), and had stage IV disease at baseline (449 [90.5%]), 17 (3.4%) patients had brain metastases, 122 (24.6%) patients had liver metastases, 409 (82.5%) patients with an ECOG performance status of one and 384 (77.4%) patients with PD-L1 tumor cells <1%.