Co-transfection of METTL3 and SLC7A11 constructs showed that SLC7A11 overexpression attenuated METTL3-induced fluorescence intensity of C11-BODIPY (Fig. 2F) and reduced sensitivity to erastin in METTL3-overexpressing cancer cells (Fig. 2G, H). Here, SLC7A11 is linked to cancer.