And also, in asthma, PPARγ plays a positive regulatory role on the accumulation of ILC2s as well as in the functioning of effector, and sex hormones can promote the expression of PPARγ protein expression and triggers asthma, which provides new clues for asthma treatment and important guidelines for the development of the disease, as well as providing new targets for disease treatment, but the negative effects of neurological damage caused by PPAR inhibition should not be ignored, and further exploration and consideration are needed. The gene discussed is PPARG; the disease is asthma.