Between 85 and 90% of gastrointestinal stromal tumours (GIST) harbour a mutation of v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) or platelet-derived growth factor receptor alpha (PDGFRa) [44], as potential LB markers Table 1. This evidence concerns the gene KIT and gastrointestinal stromal tumor.