The sensitivity, specificity, PPV, and NPV were calculated for GPC1 IHC marker in the 68 studied cases of NSCLC, and it was found that the sensitivity of GPC1 was 97.2%, specificity was 84.4%, PPV was 87.5%, NPV was 96.4%, and overall accuracy was 91.2%. Here, GPC1 is linked to non-small cell lung carcinoma.