Vita R et al. analyzed 66 patients with pubertal gynecomastia and 40 controls, finding LH levels 31% higher in patients (4.93 ± 1.88 vs. 3.77 ± 1.74 mIU/mL, p = 0.019), though within the normal range. This evidence concerns the gene PLOD1 and Gynecomastia.