According to the research results, the genotypes of polymorphisms rs9934438 and rs9923231 in the VKORC1 gene, rs5918 in the ITGB3 gene, and rs2070959 in the UGT1A6 gene were significantly associated with complications in HF patients (p < 0.05) [14]. This evidence concerns the gene VKORC1 and hydrops fetalis.