Notably, EGFR also clusters with another group regulating cell cycle, cell growth, tumor suppression, OS, cellular stress response, apoptosis, senescence, transcription, metabolism, and including the transcription factor CEBPA (this contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of its target genes (modulating gene expression in cell cycle regulation). The gene discussed is EGFR; the disease is neoplasm.