EGFR and neoplasm: These molecular analyses seamlessly integrate with advanced imaging modalities—such as FDG-PET, EGFR-targeted tracers, and somatostatin receptor imaging for neuroendocrine tumors—leading to more accurate delineation of tumor borders, better identification of candidates for parenchyma-sparing procedures, and opportunities for bronchovascular or vascular reconstruction techniques to avoid extensive resections like pneumonectomy.