Figure 6B shows that the ectopic expression of J-PKAc repressed the expression of FCN3, MBL2, and MAC members, suggesting that similar repression might take place in fusion-positive HBLs. To further examine the role of J-PKAc in the reduction in the expression of MAC members and in the expansion of fusion-expressing cells, we examined the mRNAs of MAC members, FCN3, and MBL2 in tumors of five patients with FLC. Figure 6C shows that the FLC patients have lower levels of FCN3 and MBL2 and low levels of members of the MAC compared to non-tumor sections that do not express the fusion kinase. This evidence concerns the gene MBL2 and neoplasm.