Specifically, MK parameters tend to exhibit higher values in HGG or gliomas with IDH wildtype compared to LGG or gliomas with IDH mutant, indicating an increase in microstructural complexity associated with malignancies, such as elevated cell proliferation, necrosis, and heterogeneous bleeding patterns, as well as cellular and myelin degradation products [80,81,82]. This evidence concerns the gene IDH1 and central nervous system cancer.