Complementarily, by predicting target genes of the deregulated miRNAs let-7c, miR-21, miR-34a, miR-126, miR-18a, miR-145, miR-221, miR-106a, miR-222, miR-143, and miR-106a in high-malignancy PCa, we identified potential modulation of genes such as UHRF2, MDM4, MET, SOX11, ERG, MYO6, GMFB, BCR, FOXS1, KIT, DMTF1, SORCS1, CCND1, STAT3, SKP2, CREBRF, MALT1, TP53INP1, RB1, E2F1, and BCL2L11 (Bim). The gene discussed is TP53INP1; the disease is posterior cortical atrophy.