SS18 and synovial sarcoma: Genetically, STS are characterised by four types of molecular alterations, either driver somatic mutations, for example, mutations in the KIT gene in GIST [3], or chromosomal translocations, which result in fusion genes such as the SS18-SSX gene fusion due to the t(X;18) (p11.2;q11.2) translocation in synovial sarcoma [4], or neochromosomes, as in the case of well-differentiated and dedifferentiated liposarcoma due to amplification of the chromosomal 12q13-15 region [5], or complex karyotypes like in the case of leiomyosarcoma [6].