The results show that the probiotic strain Al-Pro (AJ3) had the lowest IFN-γ/IL-10 ratio and IFN-γ secretion compared to other formulations, indicating its potential effectiveness in reducing autoimmunity and protecting motor neurons in ALS by modulating IFN-γ levels and immune cell activity [184]. The gene discussed is IFNG; the disease is amyotrophic lateral sclerosis.