The mechanisms proposed to account for the fall risk and vitamin D insufficiency relationship typically focus on factors, including impaired muscle function due to vitamin D receptor-mediated effects on muscle cells [46], reduced bone integrity from secondary hyperparathyroidism, leading to increased bone resorption [47], and vitamin D deficiency-induced inflammation that may exacerbate neurological a neuromuscular dysfunction [48]. This evidence concerns the gene VDR and secondary hyperparathyroidism.