One study, comprising 25 postmenopausal T2DM patients treated with Cinnamomum cassia 1.5 g/day or placebo for 6 weeks, showed that FPG, FPI, HbA1c, HOMA-IR, composite index of insulin sensitivity (ISIcomp), and oral glucose insulin sensitivity (OGIS) were not modified after supplementation [60]. The gene discussed is INS; the disease is type 2 diabetes mellitus.