The KEGG enrichment analysis revealed that Lp–FOS intervention changed many metabolic pathways, such as glycine, serine, and threonine metabolism, butanoate metabolism, glyoxylate and dicarboxylate metabolism, the biosynthesis of cofactors, glycerophospholipid metabolism, central carbon metabolism in cancer, the glucagon signaling pathway, the citrate cycle (TCA cycle), alanine, aspartate, and glutamate metabolism, and D-Amino acid metabolism. The gene discussed is FOS; the disease is cancer.