Moreover, miR-10b-5p promotes glioma cell invasion by downregulating HOXD10 and upregulating invasion factors such as MMP14 and uPAR, highlighting the miR-10b-5p/HOXD10/MMP14/uPAR axis as a key driver of glioma malignancy [66]. Here, HOXD10 is linked to central nervous system cancer.