In addition, Wang, Y et al. [26] reported that THBS1 is a potential target gene of METTL14 that functions as a tumour suppressor in prostate cancer (PCa), demonstrating that METTL14 inhibits THBS1 expression in the nucleus in an m6A-dependent manner and promotes PCa proliferation. Here, METTL14 is linked to Familial prostate cancer.