Furthermore, we investigate the relationship between cytokine level changes (IL-17, BAFF, IFN-γ, and TGF-β1) and independent variables, including demographic (gender, age), behavioral (tobacco use), clinical (schizophrenia type, disease course, disease onset, prior treatment), and biological (CRP, ESR) factors, as well as standardized assessment scores. This evidence concerns the gene IFNG and schizophrenia.