Furthermore, we investigate the relationship between cytokine level changes (IL-17, BAFF, IFN-γ, and TGF-β1) and independent variables, including demographic (gender, age), behavioral (tobacco use), clinical (schizophrenia type, disease course, disease onset, prior treatment), and biological (CRP, ESR) factors, as well as standardized assessment scores. The gene discussed is TGFB1; the disease is schizophrenia.