Additionally, cisplatin significantly decreased renal glutathione (GSH) content and superoxide dismutase (SOD) activity compared to HC rats (Figure 4H,I; p < 0.01), with additional decrease in CIN + PAG group in comparison with CIN rats (Figure 4H; p < 0.05). The gene discussed is SOD1; the disease is cervical squamous intraepithelial neoplasia.