Administration of PAG to CIN rats raised the levels of plasma IL-6 and TNF-α significantly relative to rats in CIN group (Figure 4B,C; p < 0.05), with a slight increase in plasma IL-1β level compared to CIN rats (Figure 4A; p > 0.05). The gene discussed is IL1B; the disease is cervical squamous intraepithelial neoplasia.