We studied the effect of resveratrol, genistein, apigenin and thymoquinone at non- toxic concentrations on the expression activation of type I IFN signaling genes (IFN-responsive genes IFI27 and OASL, and IFN regulatory factor IRF1) in another cell line, T47D (human breast cancer cells). Here, IFNA1 is linked to breast carcinoma.