In a similar sized cohort of women classified as obese with PCOS (n = 23), Lewandowski, Komorowski, O’Callaghan, Tan, Chen, Prelevi and Randeva [28] observed higher serum levels of MMP-2, MMP-9, and TIMP-1 but not TIMP-2. The gene discussed is TIMP2; the disease is polycystic ovary syndrome.