The 137 subjects with PCOS and 97 controls were age-matched, but the subjects with PCOS had a greater BMI (33 versus 25 kg/m2; p < 0.0001), increased HOMA-IR (2.6 versus 1.3; p < 0.005), and increased C-reactive protein (CRP, an inflammatory marker) (3.1 versus 1.0 mg/L; p = 0.0008). This evidence concerns the gene CRP and polycystic ovary syndrome.