The targets it focuses on are glycemia (FPG), insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), aspartate and alanine aminotransferases (ASTs and ALTs), C-reactive protein (CRP), thiobarbituric acid reactive substance (TBARS), stiffness, controlled attenuation parameter (CAP), dietary daily intake, and physical activity at baseline and end of treatment. This evidence concerns the gene CRP and Insulin resistance.