TGFB1 and liver cancer: The model has an accuracy level at Radjust2=0.9829 with a p-value < 10−58, as shown in Figure 4E. Similarly, for liver cancer with HBV infection, we have the following regression model:(7)ypx=1.21∗f1x−4.87∗10−3∗f2x+34.37∗f1x∗f2x+5.15∗10−1∗f3x−2.21∗10−3∗f1x∗f3x−289.11where f1x is the age-dependent distribution of risks for liver cancer, f2x is the age-dependent distribution of HBV infection rates, and f3x is the age-dependent distribution of the blood level of TGFβ1.