DCN and neoplasm: Fibroblasts forming extracellular matrix components of fibroids (Table 2, Figure 3) possess myofibroblast characteristics, with a high level of expression of ECM remodeling genes, i.e., MYH11, MYL9, or DCN and, as a result of paracrine mechanisms, the secretion of soluble growth factors are involved in the promotion of tumor growth [94].