CD274 and cancer: Furthermore, SCL2A1 plays a crucial role in tumor glucose transport and metabolism [106,107], and B4GALT1, an N-glycan synthesis-related gene, facilitates N-glycosylation by catalyzing the transfer of β-1,4-linked galactose residues to acceptor sugar molecules and, which through N-linked glycosylation of PD-L1, assists cancer immune evasion [108].