That being said, 44 proteins in our dataset were so strongly sex linked that differentiation did not change their regulation, and in females, a higher percentage of these proteins were connected to risk of coronary artery disease or acute coronary syndrome (ARVCF, GYG2, PRCP, CTPS2, RAP2C) [87,88,89,90,91], which with further testing could relate to core intrinsic resiliency among females. The gene discussed is RAP2C; the disease is acute coronary syndrome.