The examination of the function of Mammalian Enhancer-of-Akt-1-7 (mEAK-7) in mTORC1 signaling reveals that S6K2 promotes cell proliferation and migration in response to mTOR activation in various cancer types, such as hepatocellular carcinoma and lymph node-positive breast cancers [39]. This evidence concerns the gene RPS6KB2 and cancer.