BST2 and viral infectious disease: Additionally, a neutralization assay using sera from the Bst2+/+ and Bst2−/− DC-vaccinated mice showed significant differences in the ability to block viral infection (84.7% neutralization by the Bst2+/+ DC-vaccinated group vs. 50.5% by the Bst2−/− DC-vaccinated group) (Figure 5D).