Furthermore, recombinant human tubulointerstitial nephritis antigen-like protein 1 (Tinagl1) has been found to bind to EGFR, thereby inhibiting the progression and metastasis of triple negative breast cancer (TNBC), suggesting that Tinagl1 may act as an effective therapeutic agent for TNBC. This evidence concerns the gene TINAGL1 and triple-negative breast carcinoma.