SCD and Alzheimer disease: In AL mice with a co-diet of ethanol and AD-induced MASH, there was a significant 6.3-fold increase in Sirius-Red content, along with 5.4-fold and 2.3-fold increases in Col 1a1 and Col 3a1 mRNA expressions, respectively (all p < 0.05 compared to those of the WT+SCD, Et (−) mice).