Furthermore, during obesity, the progression of vascular endothelial dysfunction is promoted, as an underlying mechanism of hypertension and subsequent damage to vital organs [85]; previous studies have shown that bovine lactoferrin has antihypertensive effects through various mechanisms, such as lowering systolic blood pressure, decreasing serum adhesion molecules, and reducing reactive oxygen species levels in the aorta. This evidence concerns the gene LTF and Hypertension.