INS and gestational diabetes: Despite that it was reported that plasma irisin levels increase transiently during and shortly after bouts of exercise [110,111], in our study, significantly higher irisin levels for colostrum of GDM-insulin treated mothers 26.95 μg/mL in comparison to colostrum of mothers, who implemented lifestyle intervention, including diet and moderate physical activity (GDM-G1 cohort) 17.59 μg/mL, were demonstrated.