IL1RL1 and heart failure: Among these biomarkers, ST2 [also known as receptor of interleukin-33 (IL-33R)], the product of the gene IL1RL1 (interleukin-1 receptor-like 1; GeneID:9173), stands out due to its demonstrated efficacy as an additional stratification factor for heart failure patients, revealing cardiac stress and fibrosis [25].