Moreover, the statistically significant correlation between high BMI and high platelets (Figure 5A), high SII (Figure 5B), high NT-proBNP (Figure 5C), and high ST2/IL-33 (Figure 5D) marks a cross-link between obesity, thrombosis, systemic inflammation, myocardial inflammation, and myocardial wall stress unrelated to 131I therapy. This evidence concerns the gene NPPB and obesity due to melanocortin 4 receptor deficiency.